The Objectives of study are to find out availability of Infrastructure and Laboratory support of Science Education at Secondary schools of Sonitpur District of Assam, India. In this study, Descriptive Survey Method was adopted. 45 Secondary Schools were used as sample where Questionnaire, Interview and Observation Method were used as tools for study. The data were analyzed in percentage Method and Bar Diagram. For Infrastructure facilities, 98.7% found Head Master/ Principal rooms,91.5% Staff rooms,96.3% office rooms, 84.4% Libraries, 43.9% Gardens,96.3% Playgrounds, 22.5% General Science Classrooms and 27.2% Teaching learning Materials. Laboratory facilities, 36.8% found Science Laboratories only and 17.7% Science Laboratories with Equipments. Infrastructure and Laboratory facilities need to be improved immediately as science cannot be taught as a theoretical Subject. Liberal Grants should be available to Secondary schools for Science Laboratories and Equipments making a quality Teaching Science in Secondary schools in future.